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  • Watercolor of a fictional midlife woman with a blank journal by a window, in mint and mulberry colors.

    HRT and Depressive Symptoms: Separating Prevention, Treatment, and Withdrawal Trials

    October 12, 2026
    Understand HRT mood studies by separating prevention, treatment, and withdrawal, with symptom thresholds, safety findings, and mental-health care.
  • A conceptual red-ochre paper heart on an ice-blue surface.

    Tirzepatide and Heart Outcomes: What SURPASS-CVOT Shows Against Dulaglutide

    October 12, 2026
    Understand SURPASS-CVOT event counts, the 95.3% confidence interval, noninferiority versus superiority, and the active dulaglutide comparison.
  • Ultramarine dumbbells and an orange towel on a gym bench.

    Creatine After Menopause: What Randomized Trials Show About Muscle and Bone

    October 12, 2026
    Explore creatine trials in older and postmenopausal women, including strength, lean tissue, bone density, walking, adherence, and fracture evidence.
  • A painted fictional older man works on a wooden puzzle beside marigold and indigo details.

    TRT and Memory: What the Testosterone Trials and TEAAM Found

    October 12, 2026
    Review randomized testosterone memory results from the Testosterone Trials and TEAAM, with limits, assessment questions, and realistic expectations.
  • A fictional woman in a forest-green jacket ties her walking shoes on a park bench.

    Tirzepatide After Lifestyle Changes: What SURMOUNT-3 Actually Tested

    October 12, 2026
    Read SURMOUNT-3 results after lifestyle intervention, with clear explanations of participant selection, additional versus total loss, and study limits.
  • Sparkling water and lime on a burgundy counter with seafoam tiles.

    Semaglutide and Alcohol Use: What the 2025 and 2026 Randomized Trials Found

    October 12, 2026
    Compare the 2025 injection and 2026 oral semaglutide alcohol trials, including mixed endpoints, small samples, safety, and established treatment options.
  • Plum and pale-gold paper collage showing a tree in three seasonal scenes.

    HRT and Heart Health: What ELITE, KEEPS, and WHI Say About Timing

    October 12, 2026
    Compare ELITE, KEEPS, and WHI timing evidence, distinguishing artery imaging from heart events and explaining current HRT treatment considerations.
  • Terracotta linocut landscape with a winding trail under a sky-blue sky.

    Long-Term Semaglutide Weight Loss: Reading STEP 5 and Four Years of SELECT

    October 12, 2026
    Explore two-year STEP 5 and four-year SELECT weight results, plateau meaning, analysis differences, tolerability, and long-term follow-up questions.
  • A fictional older man in a petrol-blue jacket walks along a seaside promenade.

    TRT, Energy, and Walking Ability: What the Testosterone Trials Measured

    October 12, 2026
    Separate TRT fatigue, mood, walking, and fall outcomes in the Testosterone Trials, including primary endpoints, secondary analyses, and monitoring.
  • A fictional midlife woman and clinician discuss a closed folder in a rose and green room.

    HRT and Breast Cancer: Understanding the Long-Term WHI Results

    October 12, 2026
    Read long-term WHI breast-cancer counts and absolute rates, separating estrogen alone from CEE plus MPA, treatment duration, and formulation limits.
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