Compounded tirzepatide is a medication prepared by a licensed pharmacy for an individual patient based on a licensed prescriber’s clinical judgment. There are FDA-approved tirzepatide products available; however, compounded formulations are not FDA approved and do not undergo FDA review for safety, effectiveness, or manufacturing quality prior to dispensing.
Who should not use compounded tirzepatide?
Do not use compounded tirzepatide if:
- You have a personal or family history of medullary thyroid carcinoma (MTC)
- You have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
- You have had a serious hypersensitivity or allergic reaction to tirzepatide or any ingredients in the formulation
- You are pregnant or planning to become pregnant
How should I use compounded tirzepatide?
Use compounded tirzepatide exactly as prescribed by your provider. Do not use more frequently or in higher doses than prescribed.
- Administer via subcutaneous injection as directed
- Rotate injection sites to reduce irritation
- Do not share needles, syringes, or injection supplies
- Maintain adequate hydration and nutritional intake
What should I tell my provider before using tirzepatide?
Tell your provider about all medications you take, including prescription, over the counter medications, vitamins, and supplements.
Tell your provider if you:
- Have a history of pancreatitis
- Have gallbladder disease
- Have diabetes or blood sugar issues
- Have kidney problems
- Have severe gastrointestinal conditions (such as gastroparesis)
- Are pregnant, planning to become pregnant, or breastfeeding
What are the most serious side effects?
If you are experiencing a medical emergency, call 911 or seek immediate medical attention.
Stop using tirzepatide and seek prompt medical care if you experience:
- Signs of allergic reaction such as swelling, rash, or difficulty breathing
- Severe abdominal pain that may radiate to the back (possible pancreatitis)
- Persistent nausea and vomiting
- Symptoms of gallbladder problems
- Changes in vision
- Signs of thyroid tumor such as a lump in the neck, hoarseness, or trouble swallowing
What are the most common side effects?
Common side effects may include:
- Nausea
- Decreased appetite
- Vomiting
- Diarrhea or constipation
- Injection site irritation
- Fatigue
- Indigestion or stomach pain
Longevity & Metabolic Use Consideration
When used at lower, controlled doses, tirzepatide may support metabolic health, glucose regulation, and cardiometabolic risk reduction. Individual response varies, and dosing should always be guided by a licensed healthcare provider.
Additional Important Information
This summary provides basic information about compounded tirzepatide but does not include all possible information or risks. Your provider can determine whether this therapy is appropriate for you. Always review the information provided with your prescription each time it is filled.